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Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis

Metadherin (MTDH) overexpression in diverse cancer types has been linked to poor clinical outcomes, but definitive genetic proof of its contributions to cancer remain incomplete. In particular, the degree to which MTDH may contribute to malignant progression in vivo is lacking. Here, we report that...

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Main Authors: Wan, Liling, Hu, Guohong, Wei, Yong, Yuan, Min, Bronson, Roderick T., Yang, Qifeng, Siddiqui, Javed, Pienta, Kenneth J., Kang, Yibin
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167565/
https://ncbi.nlm.nih.gov/pubmed/25074613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1349
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