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Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.

Gene targeting allows precise, predetermined changes to be made in a chosen gene in the mouse genome. To date, targeting has been used most often for generation of animals completely lacking the product of a gene of interest. The resulting "knockout" mice have confirmed some hypotheses, ha...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Smithies, O, Maeda, N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC41675/
https://ncbi.nlm.nih.gov/pubmed/7777495
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