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Ligand-Induced Protein Responses and Mechanical Signal Propagation Described by Linear Response Theories
In this study, a general linear response theory (LRT) is formulated to describe time-dependent and -independent protein conformational changes upon CO binding with myoglobin. Using the theory, we are able to monitor protein relaxation in two stages. The slower relaxation is found to occur from 4.4 t...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
The Biophysical Society
2014
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167303/ https://ncbi.nlm.nih.gov/pubmed/25229149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.049 |
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