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Ligand-Induced Protein Responses and Mechanical Signal Propagation Described by Linear Response Theories

In this study, a general linear response theory (LRT) is formulated to describe time-dependent and -independent protein conformational changes upon CO binding with myoglobin. Using the theory, we are able to monitor protein relaxation in two stages. The slower relaxation is found to occur from 4.4 t...

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Bibliografische gegevens
Hoofdauteurs: Yang, Lee-Wei, Kitao, Akio, Huang, Bang-Chieh, Gō, Nobuhiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167303/
https://ncbi.nlm.nih.gov/pubmed/25229149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.049
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