Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo.

Retrovirus-mediated gene transfer into hepatocytes in vivo results in long-term gene expression. Limitations include the need to remove two-thirds of the liver and the relatively low frequency of gene transfer. To increase gene transfer without surgical hepatectomy, mouse hepatocytes were transduced...

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Bibliografiske detaljer
Main Authors: Lieber, A, Vrancken Peeters, M J, Meuse, L, Fausto, N, Perkins, J, Kay, M A
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41672/
https://ncbi.nlm.nih.gov/pubmed/7597103
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