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Highly efficient genome editing via 2A-coupled co-expression of two TALEN monomers
BACKGROUND: Transcription activator-like effector nucleases (TALENs) are a useful tool for targeted gene editing. TALEN monomers are traditionally expressed from two different plasmids. Each encodes a different TALEN arm that binds to a user-defined sequence and mediates gene editing. Expression of...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167141/ https://ncbi.nlm.nih.gov/pubmed/25204665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-628 |
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