The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard

The cornea is highly sensitive to oxidative stress, a process that can lead to lipid peroxidation. Ultraviolet light B (UVB) and nitrogen mustard (mechlorethamine) are corneal toxicants known to induce oxidative stress. Using a rabbit air-lifted corneal organ culture model, the oxidative stress resp...

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Autores principales: Zheng, Ruijin, Po, Iris, Mishin, Vladimir, Black, Adrienne T., Heck, Diane E., Laskin, Debra L., Sinko, Patrick J., Gerecke, Donald R., Gordon, Marion K., Laskin, Jeffrey D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167050/
https://ncbi.nlm.nih.gov/pubmed/23845594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.06.025
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