Loading...

PTEN is a protein tyrosine phosphatase for IRS1

The biological function of the PTEN tumor suppressor is mainly attributed to its lipid phosphatase activity. This study demonstrates that mammalian PTEN is a protein tyrosine phosphatase that selectively dephosphorylates insulin receptor substrate-1 (IRS1), a mediator of insulin and IGF signals. IGF...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Shi, Yuji, Wang, Junru, Chandarlapaty, Sarat, Cross, Justin, Thompson, Craig, Rosen, Neal, Jiang, Xuejun
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167033/
https://ncbi.nlm.nih.gov/pubmed/24814346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2828
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!