Wordt geladen...

PTEN is a protein tyrosine phosphatase for IRS1

The biological function of the PTEN tumor suppressor is mainly attributed to its lipid phosphatase activity. This study demonstrates that mammalian PTEN is a protein tyrosine phosphatase that selectively dephosphorylates insulin receptor substrate-1 (IRS1), a mediator of insulin and IGF signals. IGF...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Shi, Yuji, Wang, Junru, Chandarlapaty, Sarat, Cross, Justin, Thompson, Craig, Rosen, Neal, Jiang, Xuejun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167033/
https://ncbi.nlm.nih.gov/pubmed/24814346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2828
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!