The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences.

The penicillin biosynthetic genes (pcbAB, pcbC, penDE) of Penicillium chrysogenum AS-P-78 were located in a 106.5-kb DNA region that is amplified in tandem repeats (five or six copies) linked by conserved TTTACA sequences. The wild-type strains P. chrysogenum NRRL 1951 and Penicillium notatum ATCC 9...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Fierro, F, Barredo, J L, Díez, B, Gutierrez, S, Fernández, F J, Martín, J F
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41670/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.6200
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