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Histone modifications and a choice of variant: a language that helps the genome express itself

Covalent post-translational modifications on histones impact chromatin structure and function. Their misfunction, along with perturbations or mutations in genes that regulate their dynamic status, has been observed in several diseases. Thus, targeting histone modifications represents attractive oppo...

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Detalhes bibliográficos
Main Authors: Gurard-Levin, Zachary A., Almouzni, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Faculty of 1000 Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166940/
https://ncbi.nlm.nih.gov/pubmed/25343033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P6-76
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