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Increased aortic stiffness elevates pulse and mean pressure and compromises endothelial function in Wistar rats

An increase in pulse pressure (PP) is highly associated with hypertension. The goal of this study was to determine the effect of increased aortic stiffness on PP and endothelial dysfunction as precursors to hypertension. A rat model of suddenly increased aortic stiffness by use of a nonconstrictive...

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Bibliografske podrobnosti
Main Authors: Guo, Xiaomei, Lu, Xiao, Yang, Junrong, Kassab, Ghassan S.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166746/
https://ncbi.nlm.nih.gov/pubmed/25038146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00265.2014
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