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Increased aortic stiffness elevates pulse and mean pressure and compromises endothelial function in Wistar rats

An increase in pulse pressure (PP) is highly associated with hypertension. The goal of this study was to determine the effect of increased aortic stiffness on PP and endothelial dysfunction as precursors to hypertension. A rat model of suddenly increased aortic stiffness by use of a nonconstrictive...

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Autori principali: Guo, Xiaomei, Lu, Xiao, Yang, Junrong, Kassab, Ghassan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166746/
https://ncbi.nlm.nih.gov/pubmed/25038146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00265.2014
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