Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na(+)/H(+) exchanger

Epidermal growth factor (EGF) is linked to the pathogenesis of polycystic kidney disease (PKD). We explored signaling pathways activated by EGF in orpk cilia (−) collecting duct cell line derived from a mouse model of PKD (hypomorph of the Tg737/Ift88 gene) with severely stunted cilia, and in a cont...

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Auteurs principaux: Coaxum, Sonya D., Blanton, Mary G., Joyner, Alisha, Akter, Tanjina, Bell, P. Darwin, Luttrell, Louis M., Raymond, John R., Lee, Mi-Hye, Blichmann, Paul A., Garnovskaya, Maria N., Saigusa, Takamitsu
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166740/
https://ncbi.nlm.nih.gov/pubmed/25055824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00188.2014
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