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Carbohydrate-to-carbohydrate interactions between α2,3-linked sialic acids on α2 integrin subunits and asialo-GM1 underlie the bone metastatic behaviour of LNCAP-derivative C4-2B prostate cancer cells

Complex interplays among proteins, lipids and carbohydrates can alter the phenotype and are suggested to have a crucial role in tumour metastasis. Our previous studies indicated that a complex of the GSLs (glycosphingolipids), AsGM1 (asialo-GM1), which lacks α2,3-linked sialic acid, and α2β1 integri...

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Detalhes bibliográficos
Main Authors: Van Slambrouck, Séverine, Groux-Degroote, Sophie, Krzewinski-Recchi, Marie-Ange, Cazet, Aurélie, Delannoy, Philippe, Steelant, Wim F. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166120/
https://ncbi.nlm.nih.gov/pubmed/25137483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140096
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