Activation of mammalian retinoid X receptors by the insect growth regulator methoprene.

We report that methoprene and its derivatives can stimulate gene transcription in vertebrates by acting through the retinoic acid-responsive transcription factors, the retinoid X receptors (RXRs). Methoprene is an insect growth regulator in domestic and agricultural use as a pesticide. At least one...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Harmon, M A, Boehm, M F, Heyman, R A, Mangelsdorf, D J
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.6157
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