Development of BODIPY FL Vindoline as a Novel and High-Affinity Pregnane X Receptor Fluorescent Probe

[Image: see text] The pregnane X receptor (PXR) regulates the metabolism and excretion of xenobiotics and endobiotics by regulating the expression of drug-metabolizing enzymes and transporters. The unique structure of PXR allows it to bind many drugs and drug leads, possibly causing undesired drug–d...

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Hlavní autoři: Lin, Wenwei, Liu, Jiuyu, Jeffries, Cynthia, Yang, Lei, Lu, Yan, Lee, Richard E., Chen, Taosheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166032/
https://ncbi.nlm.nih.gov/pubmed/25133934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc5002856
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