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The CD70-CD27 Axis, a New Brake in the T Helper 17 Cell Response
The CD70-CD27 interaction is known to positively regulate T cell expansion and effector function by providing costimulatory signals. In this issue of Immunity, Coquet et al. (2013) show an unexpected T-helper-17-cell-specific negative regulation mediated by CD70-CD27 interaction.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165643/ https://ncbi.nlm.nih.gov/pubmed/23352216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.01.005 |
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