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Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP

[Image: see text] A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when em...

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Detalhes bibliográficos
Main Authors: Gao, Angela X., Liao, Longyan, Johnson, Jeremiah A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165536/
https://ncbi.nlm.nih.gov/pubmed/25243099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mz5004097
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