A systems biology approach reveals a link between systemic cytokines and skeletal muscle energy metabolism in a rodent smoking model and human COPD

BACKGROUND: A relatively large percentage of patients with chronic obstructive pulmonary disease (COPD) develop systemic co-morbidities that affect prognosis, among which muscle wasting is particularly debilitating. Despite significant research effort, the pathophysiology of this important extrapulm...

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Autori principali: Davidsen, Peter K, Herbert, John M, Antczak, Philipp, Clarke, Kim, Ferrer, Elisabet, Peinado, Victor I, Gonzalez, Constancio, Roca, Josep, Egginton, Stuart, Barberá, Joan A, Falciani, Francesco
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165371/
https://ncbi.nlm.nih.gov/pubmed/25228925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0059-5
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