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Hyperosmolar Tears Enhance Cooling Sensitivity of the Corneal Nerves in Rats: Possible Neural Basis for Cold-Induced Dry Eye Pain

PURPOSE. Tear hyperosmolarity is a ubiquitous feature of dry-eye disease. Although dry-eye patients' sensitivity to cooling is well known, the effects of tear hyperosmolarity on a small amount of cooling in the corneal nerves have not been quantitatively examined. Recently reported corneal affe...

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Autors principals: Hirata, Harumitsu, Rosenblatt, Mark I.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165368/
https://ncbi.nlm.nih.gov/pubmed/25139732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14642
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