The Antibody Genetics of Multiple Sclerosis: Comparing Next-Generation Sequencing to Sanger Sequencing

We previously identified a distinct mutation pattern in the antibody genes of B cells isolated from cerebrospinal fluid (CSF) that can identify patients who have relapsing-remitting multiple sclerosis (RRMS) and patients with clinically isolated syndromes who will convert to RRMS. This antibody gene...

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Main Authors: Rounds, William H., Ligocki, Ann J., Levin, Mikhail K., Greenberg, Benjamin M., Bigwood, Douglas W., Eastman, Eric M., Cowell, Lindsay G., Monson, Nancy L.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165282/
https://ncbi.nlm.nih.gov/pubmed/25278930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2014.00166
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