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Stem cell senescence. Effects of REAC technology on telomerase-independent and telomerase-dependent pathways
Decline in the gene expression of senescence repressor Bmi1, and telomerase, together with telomere shortening, underlay senescence of stem cells cultured for multiple passages. Here, we investigated whether the impairment of senescence preventing mechanisms can be efficiently counteracted by exposu...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165271/ https://ncbi.nlm.nih.gov/pubmed/25224681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06373 |
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