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Nef Stimulates Human Immunodeficiency Virus Type 1 Replication in Primary T Cells by Enhancing Virion-Associated gp120 Levels: Coreceptor-Dependent Requirement for Nef in Viral Replication

The Nef protein enhances human immunodeficiency virus type 1 (HIV-1) replication through an unknown mechanism. We and others have previously reported that efficient HIV-1 replication in activated primary CD4(+) T cells depends on the ability of Nef to downregulate CD4 from the cell surface. Here we...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Lundquist, Christopher A., Zhou, Jing, Aiken, Christopher
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15163722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.12.6287-6296.2004
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