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Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export

Mechanisms for exporting variably sized cargo from the endoplasmic reticulum (ER) using the same machinery remain poorly understood. COPII-coated vesicles, which transport secretory proteins from the ER to the Golgi apparatus, are typically 60–90 nm in diameter. However, collagen, which forms a trim...

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Bibliografiske detaljer
Main Authors: Saito, Kota, Yamashiro, Koh, Shimazu, Noriko, Tanabe, Tomoya, Kontani, Kenji, Katada, Toshiaki
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164946/
https://ncbi.nlm.nih.gov/pubmed/25202031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201312062
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