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Ghrelin Induces Leptin Resistance by Activation of Suppressor of Cytokine Signaling 3 Expression in Male Rats: Implications in Satiety Regulation

The anorexigenic adipocyte-derived hormone leptin and the orexigenic hormone ghrelin act in opposition to regulate feeding behavior via the vagal afferent pathways. The mechanisms by which ghrelin exerts its inhibitory effects on leptin are unknown. We hypothesized that ghrelin activates the exchang...

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Main Authors: Heldsinger, Andrea, Grabauskas, Gintautas, Wu, Xiaoyin, Zhou, ShiYi, Lu, Yuanxu, Song, Il, Owyang, Chung
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164930/
https://ncbi.nlm.nih.gov/pubmed/25060362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2095
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