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Synthesis of a thymidyl pentamer of deoxyribonucleic guanidine and binding studies with DNA homopolynucleotides.

Replacement of the phosphodiester linkages of the polyanion DNA with guanidine linkers provides the polycation deoxynucleic guanidine (DNG). The synthesis of pentameric thymidyl DNA is provided. This polycationic DNG species binds with unprecedented affinity and with base-pair specificity to negativ...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Dempcy, R O, Browne, K A, Bruice, T C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597087/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.6097
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