Amino Acid Sequence and Structural Comparison of BACE1 and BACE2 Using Evolutionary Trace Method

Beta-amyloid precursor protein cleavage enzyme 1 (BACE1) and beta-amyloid precursor protein cleavage enzyme 2 (BACE2), members of aspartyl protease family, are close homologues and have high similarity in their protein crystal structures. However, their enzymatic properties differ leading to dispara...

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Autori principali: Mirsafian, Hoda, Mat Ripen, Adiratna, Merican, Amir Feisal, Mohamad, Saharuddin Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164807/
https://ncbi.nlm.nih.gov/pubmed/25254246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/482463
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