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Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age

INTRODUCTION: In the human demyelinating central nervous system (CNS) disease multiple sclerosis, remyelination promotes recovery and limits neurodegeneration, but this is inefficient and always ultimately fails. Furthermore, these regenerated myelin sheaths are thinner and shorter than the original...

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Auteurs principaux: Münzel, Eva Jolanda, Becker, Catherina G, Becker, Thomas, Williams, Anna
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164766/
https://ncbi.nlm.nih.gov/pubmed/25022486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0077-y
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