c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells

BACKGROUND: Hard consistency, developed under the influence of tumor cell factors, is a characteristic feature of a breast tumor. Activation of resident fibroblasts leading to a myofibroblast phenotype is the principal feature that orchestrates this fibrotic process. The aim of this study was to ass...

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Bibliografiske detaljer
Main Authors: Tobar, Nicolás, Toyos, Marcela, Urra, Carla, Méndez, Nicolás, Arancibia, Rodrigo, Smith, Patricio C, Martínez, Jorge
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164761/
https://ncbi.nlm.nih.gov/pubmed/25175743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-640
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