Notch Signaling May Be Involved in the Abnormal Differentiation of Epidermal Keratinocytes in Psoriasis

Localization of each keratin isoform differs among epidermal layers. Proliferating basal cells synthesize keratin 14 (K14) and suprabasal cells express keratin 10 (K10) in normal skin. Notch signaling is essential for keratinocyte differentiation. Notch1 is expressed in all epidermal layers, Notch2...

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Detalhes bibliográficos
Main Authors: Ota, Tami, Takekoshi, Susumu, Takagi, Tatsuya, Kitatani, Kanae, Toriumi, Kentaro, Kojima, Tomoko, Kato, Masayuki, Ikoma, Norihiro, Mabuchi, Tomotaka, Ozawa, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164705/
https://ncbi.nlm.nih.gov/pubmed/25392571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.14027
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