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Thiol-ene hydrogels as desmoplasia-mimetic matrices for modeling pancreatic cancer cell growth, invasion, and drug resistance

The development of pancreatic ductal adenocarcinoma (PDAC) is heavily influenced by local stromal tissues, or desmoplasia. Biomimetic hydrogels capable of mimicking tumor niches are particularly useful for discovering the role of independent matrix cues on cancer cell development. Here, we report a...

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Detalhes bibliográficos
Main Authors: Ki, Chang Seok, Lin, Tsai-Yu, Korc, Murray, Lin, Chien-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164606/
https://ncbi.nlm.nih.gov/pubmed/25176061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.08.014
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