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A surplus of positive trials: weighing biases and reconsidering equipoise

In this issue, Fries and Krishnan raise provocative new ideas to explain the surfeit of positive industry sponsored trials evaluating new drugs. They suggest that these trials were designed after so much preliminary work that they were bound to be positive (design bias) and that this violates clinic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Felson, David T, Glantz, Leonard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC416455/
https://ncbi.nlm.nih.gov/pubmed/15142261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1189
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