Cytochrome P450 Monooxygenase CYP53 Family in Fungi: Comparative Structural and Evolutionary Analysis and Its Role as a Common Alternative Anti-Fungal Drug Target

Cytochrome P450 monooxygenases (CYPs/P450s) are heme-thiolate proteins whose role as a drug target against pathogenic microbes has been explored because of their stereo- and regio-specific oxidation activity. We aimed to assess the CYP53 family's role as a common alternative drug target against...

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Detalhes bibliográficos
Main Authors: Jawallapersand, Poojah, Mashele, Samson Sitheni, Kovačič, Lidija, Stojan, Jure, Komel, Radovan, Pakala, Suresh Babu, Kraševec, Nada, Syed, Khajamohiddin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164535/
https://ncbi.nlm.nih.gov/pubmed/25222113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107209
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