Mitotic phosphorylation of SUN1 loosens its connection with the nuclear lamina while the LINC complex remains intact

At the onset mitosis in higher eukaryotes, the nuclear envelope (NE) undergoes dramatic deconstruction to allow separation of duplicated chromosomes. Studies have shown that during this process of nuclear envelope breakdown (NEBD), the extensive protein networks of the nuclear lamina are disassemble...

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Detalhes bibliográficos
Main Authors: Patel, Jennifer T, Bottrill, Andrew, Prosser, Suzanna L, Jayaraman, Sangeetha, Straatman, Kees, Fry, Andrew M, Shackleton, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164488/
https://ncbi.nlm.nih.gov/pubmed/25482198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.36232
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