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Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development
The concept of 'equipoise', or the 'uncertainty principle', has been represented as a central ethical principle, and holds that a subject may be enrolled in a randomized controlled trial (RCT) only if there is true uncertainty about which of the trial arms is most likely to benef...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC416446/ https://ncbi.nlm.nih.gov/pubmed/15142271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1170 |
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