Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development
The concept of 'equipoise', or the 'uncertainty principle', has been represented as a central ethical principle, and holds that a subject may be enrolled in a randomized controlled trial (RCT) only if there is true uncertainty about which of the trial arms is most likely to benefit the patient. We s...
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| Publicado no: | Arthritis Res Ther |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15142271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar1170 |
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