Abl Interactor 1 (Abi-1) Wave-Binding and SNARE Domains Regulate Its Nucleocytoplasmic Shuttling, Lamellipodium Localization, and Wave-1 Levels

The Abl interactor 1 (Abi-1) protein has been implicated in the regulation of actin dynamics and localizes to the tips of lamellipodia and filopodia. Here, we show that Abi-1 binds the actin nucleator protein Wave-1 through an amino-terminal Wave-binding (WAB) domain and that disruption of the Abi-1...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Echarri, Asier, Lai, Margaret J., Robinson, Matthew R., Pendergast, Ann Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15143189/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.11.4979-4993.2004
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