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Cohesin gene mutations in tumorigenesis: from discovery to clinical significance

Cohesin is a multi-protein complex composed of four core subunits (SMC1A, SMC3, RAD21, and either STAG1 or STAG2) that is responsible for the cohesion of sister chromatids following DNA replication until its cleavage during mitosis thereby enabling faithful segregation of sister chromatids into two...

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Detalles Bibliográficos
Autores principales: Solomon, David A., Kim, Jung-Sik, Waldman, Todd
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163871/
https://ncbi.nlm.nih.gov/pubmed/24856830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2014.47.6.092
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