Impact of Linaclotide Treatment on Work Productivity and Activity Impairment in Adults with Irritable Bowel Syndrome with Constipation: Results from 2 Randomized, Double-Blind, Placebo-Controlled Phase 3 Trials

BACKGROUND: Irritable bowel syndrome with constipation (IBS-C), a chronic functional gastrointestinal disorder, has been shown to negatively affect work productivity and impair daily activity, resulting in a substantial burden for patients and employers. Linaclotide is a first-in-class guanylate cyc...

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Главные авторы: Buono, Jessica L., Tourkodimitris, Stavros, Sarocco, Phil, Johnston, Jeffrey M., Carson, Robyn T.
Формат: Artigo
Язык:Inglês
Опубликовано: Engage Healthcare Communications, LLC 2014
Предметы:
Clinical
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163780/
https://ncbi.nlm.nih.gov/pubmed/25237424
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