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Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada

BACKGROUND: PALB2 has emerged as a breast cancer susceptibility gene. Mutations in PALB2 have been identified in almost all breast cancer populations studied to date, but the rarity of these mutations and lack of information regarding their penetrance makes genetic counseling for these families chal...

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Κύριοι συγγραφείς:	Hartley, Taila, Cavallone, Luca, Sabbaghian, Nelly, Silva-Smith, Rachel, Hamel, Nancy, Aleynikova, Olga, Smith, Erika, Hastings, Valerie, Pinto, Pedro, Tischkowitz, Marc, Tomiak, Eva, Foulkes, William D
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BioMed Central 2014
Θέματα:	Research
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4163678/ https://ncbi.nlm.nih.gov/pubmed/25225577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-12-19
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Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada

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