Theranostic Unimolecular Micelles Based on Brush-Shaped Amphiphilic Block Copolymers for Tumor-Targeted Drug Delivery and Positron Emission Tomography Imaging

[Image: see text] Brush-shaped amphiphilic block copolymers were conjugated with a monoclonal antibody against CD105 (i.e., TRC105) and a macrocyclic chelator for (64)Cu-labeling to generate multifunctional theranostic unimolecular micelles. The backbone of the brush-shaped amphiphilic block copolym...

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Bibliographic Details
Main Authors: Guo, Jintang, Hong, Hao, Chen, Guojun, Shi, Sixiang, Nayak, Tapas R., Theuer, Charles P., Barnhart, Todd E., Cai, Weibo, Gong, Shaoqin
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163544/
https://ncbi.nlm.nih.gov/pubmed/24628452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/am5002585
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