LRRK2 G2385R and R1628P Mutations Are Associated with an Increased Risk of Parkinson's Disease in the Malaysian Population

The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk o...

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Main Authors: Gopalai, Aroma Agape, Lim, Shen-Yang, Chua, Jing Yi, Tey, Shelisa, Lim, Thien Thien, Mohamed Ibrahim, Norlinah, Tan, Ai Huey, Eow, Gaik Bee, Abdul Aziz, Zariah, Puvanarajah, Santhi Datuk, Viswanathan, Shanthi, Looi, Irene, Lim, Soo Kun, Tan, Li Ping, Chong, Yip Boon, Tan, Chong Tin, Zhao, Yi, Tan, E. K., Ahmad-Annuar, Azlina
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Publishing Corporation 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163406/
https://ncbi.nlm.nih.gov/pubmed/25243190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/867321
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