Lentivirus Mediated siRNA against GluN2B Subunit of NMDA Receptor Reduces Nociception in a Rat Model of Neuropathic Pain

Although neuropathic pain (NP) is still not fully understood by scientists and clinicians alike, studies suggest that N-methyl-D-aspartate (NMDA) receptors play an important role in the induction and maintenance of NP. A promising treatment for NP is through the downregulation of NMDA subunit GluN2B...

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Hlavní autoři: Wu, Feixiang, Pan, Ruirui, Chen, Jiaying, Sugita, Megumi, Chen, Caiyang, Tao, Yong, Yu, Weifeng, Sun, Yuming
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163390/
https://ncbi.nlm.nih.gov/pubmed/25243192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/871637
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