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Fructose-1, 6-bisphosphatase opposes renal carcinoma progression

Clear cell renal cell carcinoma (ccRCC), the most frequent form of kidney cancer(1), is characterized by elevated glycogen and fat deposition(2). These consistent metabolic alterations are associated with normoxic stabilization of hypoxia inducible factors (HIFs)(3), secondary to von hippel-lindau (...

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Detalles Bibliográficos
Main Authors: Li, Bo, Qiu, Bo, Lee, David S.M., Walton, Zandra E., Ochocki, Joshua D., Mathew, Lijoy K., Mancuso, Anthony, Gade, Terence P.F., Keith, Brian, Nissim, Itzhak, Simon, M. Celeste
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162811/
https://ncbi.nlm.nih.gov/pubmed/25043030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13557
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