Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

BACKGROUND: Multi-walled carbon nanotubes (MWCNTs) pose a possible human health risk for lung disease as a result of inhalation exposure. Mice exposed to MWCNTs develop pulmonary fibrosis. Lung macrophages engulf MWCNTs and produce pro-fibrogenic cytokines including interleukin (IL)-1β, IL-6, tumor...

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Hlavní autoři: Taylor, Alexia J., McClure, Christina D., Shipkowski, Kelly A., Thompson, Elizabeth A., Hussain, Salik, Garantziotis, Stavros, Parsons, Gregory N., Bonner, James C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162563/
https://ncbi.nlm.nih.gov/pubmed/25216247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106870
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