Induction of Body Weight Loss through RNAi-Knockdown of APOBEC1 Gene Expression in Transgenic Rabbits

In the search of new strategies to fight against obesity, we targeted a gene pathway involved in energy uptake. We have thus investigated the APOB mRNA editing protein (APOBEC1) gene pathway that is involved in fat absorption in the intestine. The APOB gene encodes two proteins, APOB100 and APOB48,...

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Detalhes bibliográficos
Main Authors: Jolivet, Geneviève, Braud, Sandrine, DaSilva, Bruno, Passet, Bruno, Harscoët, Erwana, Viglietta, Céline, Gautier, Thomas, Lagrost, Laurent, Daniel-Carlier, Nathalie, Houdebine, Louis-Marie, Harosh, Itzik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162549/
https://ncbi.nlm.nih.gov/pubmed/25216115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106655
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