Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis

We recently reported that young (3 to 4 months old) mice lacking Exon 1 of the Smad7 gene (S7ΔEx1 mice) show enhanced proliferation of neural stem and progenitor cells (NPCs) in the hippocampal dentate gyrus (DG) and in the subventricular zone (SVZ) of the lateral ventricles. It remained unclear, ho...

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Detalhes bibliográficos
Main Authors: Marschallinger, Julia, Krampert, Monika, Couillard-Despres, Sebastien, Heuchel, Rainer, Bogdahn, Ulrich, Aigner, Ludwig
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2014
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162458/
https://ncbi.nlm.nih.gov/pubmed/24862634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.05.011
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