A phase I study of sunitinib combined with modified FOLFOX6 in patients with advanced solid tumors

PURPOSE: This phase I study assessed the safety, tolerability, maximum tolerated dose (MTD), pharmacokinetics, and preliminary antitumor effects of sunitinib combined with modified FOLFOX6 (mFOLFOX6). METHODS: Patients with advanced solid malignancies received mFOLFOX6 in 2-week cycles with escalati...

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Detalhes bibliográficos
Main Authors: Leong, S., Eckhardt, S. G., Chan, E., Messersmith, W. A., Spratlin, J., Camidge, D. R., Diab, S., Khosravan, R., Lin, X., Maneval, E. Chow, Lockhart, A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162394/
https://ncbi.nlm.nih.gov/pubmed/22623210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1880-4
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