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Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters
Transporters are ubiquitous proteins mediating the translocation of solutes across cell membranes, a biological process involved in nutrition, signaling, neurotransmission, cell communication and drug uptake or efflux. Similarly to enzymes, most transporters have a single substrate binding-site and...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2014
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162363/ https://ncbi.nlm.nih.gov/pubmed/25309439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00207 |
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