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Cell Surface Epidermal Growth Factor Receptors Increase Src and c-Cbl Activity and Receptor Ubiquitylation

There is an established role for the endocytic pathway in regulation of epidermal growth factor receptor (EGFR) signaling to downstream effectors. However, because ligand-mediated EGFR endocytosis utilizes multiple “moving parts,” dissecting the spatial versus temporal contributions has been challen...

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Autors principals: Parks, Eileen E., Ceresa, Brian P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162159/
https://ncbi.nlm.nih.gov/pubmed/25074934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579581
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