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Alternative Calibration Strategies for the Clinical Laboratory: Application to Nortriptyline Therapeutic Drug Monitoring

BACKGROUND: The addition of a calibration curve with every run is both time-consuming and expensive for clinical mass spectrometry assays. We present alternative calibration strategies that eliminate the need for a calibration curve except as required by laboratory regulations. METHODS: We measured...

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Detalhes bibliográficos
Main Authors: Olson, Matthew T., Breaud, Autumn, Harlan, Robert, Emezienna, Nkechinyere, Schools, Sabitha, Yergey, Alfred L., Clarke, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162085/
https://ncbi.nlm.nih.gov/pubmed/23426427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2012.194639
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