The trifunctional antibody catumaxomab amplifies and shapes tumor-specific immunity when applied to gastric cancer patients in the adjuvant setting

Background: Patients with gastric cancer benefit from perioperative chemotherapy, however, treatment is toxic and many patients will relapse. The trifunctional antibody catumaxomab targets EpCAM on tumor cells, CD3 on T cells, and the Fcγ-receptor of antigen-presenting cells. While in Europe catumax...

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Main Authors: Atanackovic, Djordje, Reinhard, Henrike, Meyer, Sabrina, Spöck, Stefanie, Grob, Tobias, Luetkens, Tim, Yousef, Sara, Cao, Yanran, Hildebrandt, York, Templin, Julia, Bartels, Katrin, Lajmi, Nesrine, Stoiber, Heribert, Kröger, Nicolaus, Atz, Judith, Seimetz, Diane, Izbicki, Jakob R, Bokemeyer, Carsten
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2013
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162043/
https://ncbi.nlm.nih.gov/pubmed/23955093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26065
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