MiR-210 is induced by Oct-2, regulates B-cells and inhibits autoantibody production()

MicroRNAs are small, non-coding RNAs that regulate gene expression post-transcriptionally. Here, we show that miR-210 is induced by Oct-2, a key transcriptional mediator of B-cell activation. Germline deletion of miR-210 results in the development of autoantibodies from 5 months of age. Overexpressi...

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Detaylı Bibliyografya
Asıl Yazarlar: Mok, Yingting, Schwierzeck, Vera, Thomas, David C., Vigorito, Elena, Rayner, Tim F., Jarvis, Lorna B., Prosser, Haydn M., Bradley, Allan, Withers, David R., Mårtensson, Inga-Lill, Corcoran, Lynn M., Blenkiron, Cherie, Miska, Eric A., Lyons, Paul A., Smith, Kenneth G.C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162006/
https://ncbi.nlm.nih.gov/pubmed/23960236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301289
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